Non Prescription Oral Flea And Tick For Dogs – Home > Prescription Medications for Pets > NexGard Flea & Tick Chewables for Dogs > NexGard Chewables for Dogs 60.1-121 lbs (1 chew) Red

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Non Prescription Oral Flea And Tick For Dogs

Home > Best Dog Medicines > NexGard Flea & Tick Chewables for Dogs > NexGard Chewables for Dogs 60.1-121 lbs (1 chew) Red

Nexgard Chewables For Dogs 60.1 121 Lbs (1 Chew)

Home > Shop by Category > Heartworm, Flea & Tick Protection > NexGard Flea & Tick Chews for Dogs > NexGard Chews for Dogs 60.1-121 lbs (1 Chew) Red

Home > Heartworm, Flea & Tick Protection > NexGard Flea & Tick Chews for Dogs > NexGard Chews for Dogs 60.1-121 lbs (1 chew) Red

Drug compounding is often thought of as the process of combining or mixing drugs to create a medication tailored to the needs of an individual patient.

NexGard Flea & Tick Chewables for dogs is an all-new, revolutionary flea and tick preventative from the makers of Frontline®, the #1 choice of veterinarians. It’s the first flea and tick killer of its kind, as it comes in a delicious, beefy soft chew that protects your dog from flea and tick infestations for 30 days. This means you don’t have to worry about messy threads or accidentally washing your dog off while bathing! It can also be taken along with your dog’s heartworm medication, seamlessly for your convenience.

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NexGard protects your pet from adult fleas by killing them before they have a chance to lay eggs, reducing the chance of a flea infestation. It also kills the American dog tick, reducing your pet’s risk of developing a deadly tick-borne disease.

NexGard kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and for the treatment and control of the black-legged tick (Ixodes scapularis), the American dog tick (Dermacentor variabilis), and the lone star tick (Amblyomma americanum). and brown dog tick (Rhipicephalus sanguineus) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds or more, for one month.

NexGard contains a completely new ingredient that is not used in other flea and tick protection. Afoxolaner, an ingredient in NexGard, is rapidly absorbed into your pet’s bloodstream where a good concentration makes your pet’s blood toxic to insects without affecting your pet’s health. Afoxolaner is gradually metabolized to ensure that it remains in the appropriate concentration in your pet’s blood for a full 30 days.

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When a flea or tick tries to feast on your pet’s blood, afoxolaner acts on their central nervous system, interfering with an important neurotransmitter that causes instant death. This means your pet gets amazing protection in one delicious bite! NexGard is a prescription-only medication, so talk to your veterinarian about using it for your pet.

Flea & Tick Seizure Risk

NexGard can be administered with or without food. Care should be taken to ensure that the dog consumes the entire dose and treated animals should be observed for several minutes to ensure that no portion of the dose is lost or rejected. If it is suspected that a dose has been missed or if vomiting occurs within two hours of administration, take another full dose again. If a dose is missed, prescribe NexGard and resume the monthly dosing schedule.

Treatment with NexGard can be started at any time of the year. In areas where fleas are common throughout the year, monthly treatment with NexGard should be continued throughout the year without interruption.

To reduce the likelihood of reinfestation with fleas, it is important to treat all animals in the household with an approved flea control product.

Not used in humans. Keep this and all medicines out of the reach of children. In case of accidental ingestion, consult a doctor immediately.

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The safe use of NexGard in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures (see ADVERSE REACTIONS).

In a well-controlled US field study involving a total of 333 households and 615 treated dogs (415 treated with afoxolaner; 200 administered active controls), no serious adverse reactions were observed with NexGard.

1% for three months of observation is presented in the following table. The most commonly reported adverse reaction was vomiting. The incidence of vomiting was generally self-limited and of short duration and decreased with subsequent doses in both groups. Five treated dogs developed anorexia during the study, and two of these dogs developed anorexia with the first dose but not with subsequent doses.

In a US field study, one dog with a history of seizures developed a seizure on the same day after the first dose and the second dose of NexGard on the same day. This dog developed a third seizure one week after the third dose. The dog remained enrolled and completed the study. Another dog with a history of seizures developed a seizure 19 days after receiving the third dose of NexGard. The dog remained enrolled and completed the study. A third dog with a history of seizures received NexGard and did not experience seizures throughout the study.

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Best Flea And Tick Prevention For Dogs (review) Of 2023

To report suspected adverse reactions, for technical assistance, or to obtain a copy of the MSDS, contact Merial at 1-888-637-4251 or www.merial.com/nexgard. For more information about adverse drug experiences with animal drugs, contact the FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth.

Afoxolaner is a member of the isoxazoline family that binds to the binding site of insect and acarin ligands to inhibit chloride channels, particularly those blocked by the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking pre- and post-synapses. Transport of chloride ions across cell membranes. Prolonged afoxolaner-induced hyperexcitability leads to uncontrolled activity of the central nervous system and death of insects and acarines. The selective toxicity of foxolaner between insects and acarines and mammals can be inferred from the different sensitivity of insect and acarine GABA receptors compared to mammalian GABA receptors.

99% efficiency for eight hours. In a separate well-controlled laboratory study, NexGard demonstrated 100% efficacy against adult fleas at 24 hours post-infestation for 35 days and was £93% effective at 12 hours post-infestation up to 21 days and 35 days. On day 28, NexGard was 81.1% effective 12 hours after infestation. Dogs in both treated and control groups infested with fleas on day 1 produced flea eggs 12 and 24 hours after treatment (0-11 eggs and 1-17 eggs in NexGard-treated dogs, and 4-90 eggs and 0-118 eggs in in control dogs, at 12 and 24 hours, respectively). At follow-up assessments after infestation, fleas in the treated group of dogs were essentially unable to produce any eggs (0-1 eggs), while fleas from control group dogs continued to produce eggs (1-141 eggs).

In a 90-day US field study conducted in households with varying severities of existing flea infestation, the efficacy of NexGard against fleas at day 30, 60, and 90 visits compared to baseline was 98.0%, 99.7%, and 99.9%, respectively.

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Collectively, data from three studies (two laboratory and one field) show that NexGard kills fleas before they lay eggs, thereby preventing further flea infestations after treatment of an existing flea infestation.

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In a safety study, NexGard was administered orally to 8- to 9-week-old beagle puppies at 1, 3, and 5 times the maximum exposure dose (6.3 mg/kg) for three treatments every 28 days, followed by three treatments. every 14 days for a total of six treatments. Sham-dosed dogs in the control group. There were no clinically relevant effects with treatment on physical examination, body weight, food consumption, clinical pathology (hematology, clinical chemistry, or coagulation tests), gross pathology, histopathology, or organ weight. Vomiting was present throughout the study at similar rates in the treated and control groups, including one dog in the 5x group that vomited four hours after treatment.

In a well-controlled field study, NexGard was used concurrently with other medications such as vaccines, anthelmintics, antibiotics (including topical), steroids, nonsteroidal anti-inflammatory drugs, anesthetics, and antihistamines. Adverse reactions have not been observed when NexGard is used concurrently with other medications.

If a dose is missed, take the usual dose of NexGard Chewables and resume the monthly dosing schedule.

Topical Flea & Tick Prevention For Dogs

NexGard Chewables require a prescription. Give the appropriate dose based on your dog’s weight. (see how to use it). If it is suspected that a dose has been missed or if vomiting occurs within two hours of administration, take another full dose again. NexGard Chewables can be administered with or without food. NexGard Chewables should be taken year-round. Treat all pets in your home to reduce the risk of flea infestation.

The most commonly reported adverse reactions include vomiting, dry/scaly skin, diarrhea, lethargy, and loss of appetite. The incidence of vomiting was generally self-limited and of short duration and decreased with subsequent doses. There are no known contraindications to the use of NexGard Chewables.

The active ingredient in NexGard Chewables is Afoxolaner. NexGard Chewables kill adult fleas and are indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of the American dog tick.

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