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Common Medications That May Cause Weight Gain

We’ve made some improvements Explore our new site layout with larger images, easier to find information, and more. 1 of 3 Next If you have ulcerative colitis (UC), you’re probably familiar with corticosteroid medications like prednisone, powerful anti-inflammatory medications that are very effective at quickly reducing inflammation during a flare-up.

According to a study published in January 2020 in the journal Lung, participants who took prednisone reported increased fatigue and weight gain. A February 2021 review in the journal Obesity found that long-term prednisone affected body weight, appetite, and body composition.

Weight gain from prednisone is often referred to as “moon face” when changes in fat deposits occur in different areas of the body, such as the base of your neck or back, around your abdomen, or fat deposits. rounder and wider.

Rudolph Bedford, MD, a gastroenterologist at Providence St. Joseph’s Health Center in Los Angeles, California, says weight gain in people taking prednisone is related to how long you’ve been taking the drug. The longer you stay on prednisone, the more likely you are to gain weight. Why does this happen? In addition to increasing appetite, prednisone also causes fluid retention, often causing swelling of the hands, feet, and legs, along with the face, Dr. Bedford says. Prednisone can also interrupt the normal sleep-wake cycle, which can lead to insufficient sleep and disruption of hormones that help regulate appetite, says Keith Scarlata, MD, a Boston-based dietitian who specializes in inflammatory bowel diseases such as UC.

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If weight gain is especially a concern, talk to your doctor about changing your drug regimen. You should never stop taking medication on your own. Steroids should be tapered gradually under the guidance of a physician. According to the Hospital for Special Surgery, rapid withdrawal of steroids can cause fatigue, joint pain, muscle stiffness, or fever.

Your doctor may prescribe another corticosteroid, such as budenoside. “This alternative is rapidly metabolized by the liver, thereby reducing the side effects associated with corticosteroids, and appears to be as effective as prednisone,” Bedford said.

In addition, using a few simple nutritional strategies while on prednisone can help you avoid the worst cases of weight gain and stay healthy overall, says Scarlata:

You don’t have to be “enough” to treat ulcerative colitis. Take this step-by-step assessment to assess how well your treatment is working.

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If you take steroids for nonsurgical colitis, you may develop osteoporosis or increased bone density. How to keep your bones strong…

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These online nutrition services, which include lots of fruits and vegetables and plant-based proteins, are great options for people with ulcerative colitis… Antidepressants, oral steroids, and hypertension medications may be to blame for the change. scale.

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If you start taking a new medication, be sure to discuss potential side effects, such as weight gain, with your healthcare team. Adobe Stock (2)

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It should come as no surprise to anyone who has watched the drug trade that many drugs come with a long list of side effects, some of which can make you want to stop taking them altogether. A common risk on these lists: weight gain. While this effect may not be dangerous in itself, depending on your health goals, high numbers on the scale can be unsettling. That’s why it’s important to be prepared, understand why weight gain might be happening, and make sure it’s not something you have to deal with. Indeed, there may be other options.

Ask Ashley Ellis, M.D., director of clinical operations at Compwell in Collierville, Tennessee, for basic information about the drug, including what it’s used for and side effects. If you’re likely to gain weight and you’re uncomfortable, ask your doctor if you can be on a lower dose or if there are other options, she says. Of course, you’ll want to maintain healthy eating and exercise habits (or start if you’re not already).

If you’re taking medication to treat anxiety or depression, whether it’s a steroid to ease arthritis pain or an antihistamine to control the swelling and sneezing of allergies, here’s how it might affect your weight.

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Medications include amitriptyline (Elavil), doxepin (Silenor), and nortriptyline (Pamelor). “As a class, these drugs can increase activity to promote weight gain,” says Jessica Nouhavandi, co-CEO and co-founder of Honeybee Health in Culver, California. If you are taking antidepressants, do not stop taking them suddenly; first consult with your doctor and come up with a plan that will best support your mental health, advises the Harvard Women’s Health Watch. If weight gain makes you want to stop taking medication, you can talk to your doctor

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